EXATEST

Non-invasive Intracellular Mineral-Electrolyte Analysis

Published Research and References

Burton B. Silver, Ph.D.  

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Most recent publication:  

Effects of Oral Magnesium Therapy on Exercise Tolerance, Exercise-Induced Chest Pain, and Quality of Life in Patients With Coronary Artery Disease.
(Full text) M. Shechter, N. B. Merz, H. Stuehlinger, J. Slany, O. Pachinger, B. Rabinowitz, Cedars-Sinai Medical Center, and the UCLA School of Medicine, Los Angeles, CA and others; all data of intracellular magnesium measurements, EXA Test, by Burton B. Silver, Ph. D at IntraCellular Diagnostics, Foster City, CA.

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1. Noninvasive Measurement of Tissue Magnesium and Correlation With Cardiac Levels, (Full Text). Mark C.P. Haigney, MD; Burton Silver, PhD; Emmanuel Tanglao, MD; Howard S. Silverman, MD; J. Donald Hill, MD; Edward Shapiro, MD; Gary Gerstenblith, MD; Steven P. Schulman, MD; Department of Medicine, Division of Cardiology, Johns Hopkins Medical Institutions; IntraCellular Diagnostics, Inc., Circulation, 1995; 92: 2190-2197.

 2. Noninvasive Measurement of Tissue Magnesium and Correlation With Cardiac Levels, (Abstract). MCP Haigney, B Silver, E.Tanglao, HS Silverman, JD Hill, E Shapiro, G Gerstenblith, SP Schulman, Department of Medicine, Division of Cardiology, Johns Hopkins Medical Institutions, IntraCellular Diagnostics, Inc., Circulation, 1995; 92: 2190-2197.

3. Oral Magnesium Therapy Improves Endothelial Function in Patients With Coronary Artery Disease, (Abstract). Michael Shechter, MD, MA; Michael Sharir, MD; Maura J. Paul Labrador, MPH; James Forrester,MD;  Burton Silver, PhD;  C. Noel Bairey Merz, MD; Cedars-Sinai Burns and Allen Research Institute, the Division of Cardiology, Department of Medicine,  Cedars- Sinai Medical Center,  UCLA School of Medicine and IntraCellular Diagnostics, Inc, Circulation 2000;102: 2353-2358.

4. Oral Magnesium Therapy Improves Endothelial Function in Patients With Coronary Artery Disease, (Full Text). Michael Shechter, MD, MA; Michael Sharir, MD; Maura J. Paul Labrador, MPH; James Forrester,MD;  Burton Silver, PhD;  C. Noel Bairey Merz, MD; Cedars-Sinai Burns and Allen Research Institute, the Division of Cardiology, Department of Medicine,  Cedars- Sinai Medical Center,  UCLA School of Medicine and IntraCellular Diagnostics, Inc., Circulation 2000;102: 2353-2358.

5. Magnesium Modulation of Calcium Uptake in Cardiac Mitochondria: An Ultrastructual Study. B.B. Silver, L.A. Sordahl; Spectrum Publications, Inc., Magnesium in Health and Disease, pp.508-513, 1980.

6. Tissue Magnesium Levels and the Arrhythmic Substrate in Humans  (Abstract). 
Haigney MC, Berger R, Schulman S, Gerstenblith G, Tunin C, SilverB, Silverman HS, Tomaselli G, Calkins H; Department of Medicine, Division of Cardiology, Johns Hopkins Medical Institutions; IntraCellular Diagnostics, Inc.; Journal of Cardiovascular Electrophysiology, Vol. 8, pp.980-986, Number 9. September 1997 .

7. Tissue Magnesium Levels and the Arrhythmic Substrate in Humans
 (Full Text). Mark C.P. Haigney, MD; Ronald Berger, MD, PhD; Steven Schulman, MD; Gary Gerstenblith, MD; Carol Tunin, PhD; Burton Silver, PhD, Howard S. Silverman, MD; Gordon Tomaselli, MD; Hugh Calkins, MD; Department of Medicine, Division of Cardiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, Johns Hopkins Medical Institutions; IntraCellular Diagnostics, Inc.; Journal of Cardiovascular Electrophysiology. Volume 8. Number 9. September 1997.

8. Loss of Cardiac Magnesium in Experimental Heart Failure Prolongs and Destabilizes Repolarization.., (Abstract). Haigney MC, Silver B, Wei S, Kaab S, Griffiths E, Berger R, Tunin R, Kass D, Fisher WG, Silverman H. Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, IntraCellular Diagnostics, Foster City, CA, J Am Coll Cardiol 1998 Mar 1;31(3):701-6.

9. Loss of Cardiac Magnesium in Experimental Heart Failure Prolongs and Destabilizes Repolarization.., (Full Text). Haigney MC, Silver B, Wei S, Kaab S, Griffiths E, Berger R, Tunin R, Kass D, Fisher WG, Silverman H Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, IntraCellular Diagnostics, Inc. Foster City, CA 94404, J Am Coll Cardiol 1998 Mar 1; 31(3): 701-6.

10. A Unique Non-Invasive Intracellular Magnesium Assay; Correlating with Cardiac Tissues, Arrhythmias, and Therapeutic Interventions. (REVIEW)
VII International Symposium on Magnesium, Athens, Greece, 1997, Burton B. Silver, Mark C.P.Haigney et al., Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, Uniformed Services University of the Health Sciences, Bethesda, MD, IntraCellular Diagnostics, Inc, Foster City, CA.

11. Effects of Simulated Microgravity on Intracellular Ion Concentrations in Sublingual Cells and Skeletal Muscle,(Full Text).
B.B. Silver, S.B. Arnaud, B.A Harris, and J Vernikos-Dannellis. IntraCellular Diagnostics Inc., Foster City, CA & NASA Ames Research Center, Moffet Field, CA 94035 Aerospace Medical Association, Washington D.C, 1989 .

12. Application of a Novel Method to Measure IntraCellular Ions as Applied to Space Flight. S.B. Arnaud & B. B. Silver, NASA Ames Research Center, Moffet Field, CA, 94035, IntraCellular Diagnostics, Inc, Foster City, CA, 94404, NASA Technology 2000 Proceedings, Washington, D.C. 1990.

13. Life Science in Space: Intracellular  Measurements of Calcium, Phosphorus Loss in Microgravity. S.B. Arnaud & B. B. Silver, NASA Ames Research Center, Moffet Field, CA, 94035, IntraCellular Diagnostics, Inc, Foster City, CA, 94404, NASA, Bone and Mineral Conference, Indianapolis, IN, 1987.

14. NASA –Russian Study :  Space Flight Effects on Intracellular Ions in Sublingual cells of Non-Human Primates. S.B. Arnaud, R. Dotsenko, P. Fung, M Navidi and B. Silver, Life Sciences Division, NASA Ames Research Center, CA 94035, Institute for Biomedical Problems, Moscow, Russia, and IntraCellular Diagnostics, Inc. Foster City, CA 94404, Aerospace Medical Association, 1994.

15. Might Patients with the Chronic Fatigue Syndrome Have Latent Tetany of Magnesium Deficiency, (Review). Mildred Seelig, MD, MPH Journal of Chronic Fatigue Syndrome, Vol. 4(2) 1998.

16. Dr. M. Haigney Lecture Notes on Arrhythmias, & Animated Link to Principles of Electro Cardiograms. 

17. Use of IntraCellular Testing (EXAtest) by Richard I Gracer, MD.

18. Review of Experience on Exatest by Mark C Haigney, MD.

19. Interpretation Guide for Users of  EXATEST Technology, 2001 .

20. Chart Indicating Advantages of EXATEST over  Other Methods of Intracellular Analysis.

21. Usefulness of Magnesium Sulfate in Stabilizing Cardiac Repolarization in Heart Failure Secondary to Ischemic Cardiomyopathy.
(Full Text). Carlos Ince,MD; Steven P. Schulman, MD; John F. Quigley,MA; Ronald D. Berger, MD; Mark Kolasa, MD; Renee Ferguson, CTT; Burton Silver, PhD; Mark C.P. Haigney; MD; The American Journal of Cardiology, Vol. 88 – Issue 3, August 1, 2001

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*Additional References, not available here in PDF.

22. Dyckner T. Wester PO. The relation between extra- and intracellular electrolytes in patients with hypokalemia and/or diuretic treatment. Acta Med Scand. Acta Med Scand. 1978;204:269-282.

23. Eisenberg MJ. Magnesium deficiency and sudden death. Am Heart J. Am Heart J. 1992; 124:544-549.

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