IntraCellular Diagnostics, Inc«  

 

 

IntraCellular Diagnostics, Inc.«

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  Proprietary Elemental X-Ray Analysis for Tissue Electrolytes

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The Power Mineral Magnesium

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Occurrence in Nature

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 Wbb01tlg.gif (2100 bytes) The Earth's crust contains approximately 2% of magnesium. Therefore, the Dolomites, for example, consist for the most part of magnesium carbonate.

 note.gif (2100 bytes)  Magnesium also exists in sea water - at least about 0.5%

 note.gif (2100 bytes)   In addition, magnesium plays a decisive part in what city dwellers are wont to associate with "pure nature." The fresh greenness of woods and meadows owes its color to chlorophyll, a complex chemical ring with magnesium as the central atom. Magnesium deficiency is therefore readily visible: the resulting chlorosis imparts a fine yellow colour to the leaves.

 

The chlorophyll molecule

 

The pigments in leaves and blood are chemically related.

Even when at first sight it seems unbelievable: i.e. the pigment in leaves and red blood corpuscles actually have something in common.

Both, chlorophyll and hemoglobin are so-called porphyrin rings.

The only difference is that the central atom in hemoglobin is iron, whereas in chlorophyll it is magnesium.

 The technical information in this web site is not intended to recommend treatment or make specific diagnosis based on such data. It is intended for professional informational purposes, (from current medical literature), to assist practitioners in choosing appropriate protocols and modalities. Decisions on patient care should be based on all laboratory tests, health histories and clinical evaluations. 

full spectrum mineral analysis

Magnesium Balance

                Mg2+reserves in the body                 

                        Bones about 60%,   Cells about 40%          

              Interstitial compartment and Serum About 1%

                   1.                            2.prot4c.jpg (71697 bytes) 

Fig. 1: Mg2+Supply. Intake with food / Absorption quotient   30 - 70%.

Fig. 2. Renal elimination: 100 mg. per day.

Fig. 3. Mg2+Reserves in the body:

  • Bones about 60%, Cells about 40%

  • Interstitial compartment and serum about 1%

  • Bound to: see figure below

 

3.

 

  full spectrum mineral analysis

Magnesium circulation within the body...

Begins with the intake of food - we cannot produce the valuable mineral alone.  After ingestion with food, the major part of the mineral has initially a good way to travel: to the small intestine.  Only then is it absorbed:

 note.gif (2100 bytes) via the active carrier transport process and

 note.gif (2100 bytes) for larger quantities, via passive diffusion.

 

Important! Interaction with iron when supplements are used: the absorption of magnesium interferes with that of iron!  In replacement therapy with both minerals, they should be taken at a 2 to 3 hour interval from one another.

 note.gif (897 bytes)The technical information in this web site is not intended to recommend treatment or make specific diagnosis based on such data. It is intended for professional informational purposes, (from current medical literature), to assist practitioners in choosing appropriate protocols and modalities. Decisions on patient care should be based on all laboratory tests, health histories and clinical evaluations.

 

What does the body do with this valuable substance?

60% of magnesium is stored in bone. Bone forms our most important stocks of magnesium and the body can call on two thirds of these stores (as 45% of the total reserves) if need be.

40% migrates into soft tissue, principally muscles and organs. Magnesium is the second most frequently occurring intracellular cation and is found mainly in the cells.

Extracellular i.e. in the interstitial fluid between the cells,  and in blood serum, only 1% of magnesium is to be found. The major part is ionized and therefore pharmacologically active and a smaller portion is bound to other substances, to citrate, for example.

The nominal value for magnesium reserves within the body is approximately  24 to 28 grams.

Magnesium is excreted via the intestines and the kidneys:

Only approximately 5% of the amount filtered by the kidneys is ultimately excreted. The major part returns to the blood vessels via the ascending limb of Henle's loop.

 

Important! Side-effect of loop diuretics: these exert their action precisely at this site and in so doing, block re-absorption of magnesium. Long-term diuretic treatment therefore frequently causes magnesium deficiency!

 note.gif (897 bytes)

 

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Reported Magnesium Requirements

note.gif (897 bytes) Even without diuretics, however, it is recommended that you monitor your current intracellular mineral status with Exatest, because we must ensure a supply of magnesium, regardless of sex and age.

note.gif (897 bytes) Magnesium requirements increase constantly in childhood and adolescence.

note.gif (897 bytes) Older teenagers need the most: youths from 15 to 19 years of age require 400 mg, adolescent girls, 350 mg per day.

note.gif (897 bytes) During adulthood, the value remains constant at 50 mg below these respective figures - this remains unchanged, even in old age.

note.gif (897 bytes) Pregnant women are, as a rule, administered magnesium routinely from the 15th week of pregnancy onwards - at least 300 mg per day. On the basis of experience, cramps, premature contractions and complications during labor are reduced in this manner.

During lactation also, magnesium replacement therapy is recommended. In this case, the requirements increase to 375 mg per day. In foods, the magnesium content is varied in its order of magnitude from one food to another. Therefore, believe it  or not, 100 g of sunflower weeds for example contain 420 mg of magnesium. A breakfast of sunflower seed bread is therefore just what the doctor ordered!

full spectrum mineral analysis

Magnesium Content

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In foods, the magnesium content is varied in its order of magnitude from one food to another. Therefore, believe it  or not, 100g of sunflower seeds for example contain 350 to 420 mg of magnesium. A breakfast of sunflower seed bread is therefore just what the doctor ordered!

Muesli enthusiasts settle for wheatgerm (308 mg per 100g), soup fans for white beans (130 mg per 100 g). Also, with a good deal of imagination, a glass of beer can be justified by the need to supply magnesium. A half litre contains at any rate 45 mg of magnesium.

None the less, there are symptoms of magnesium deficiency. These result, among other things, from acid rain!

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The Origins of Magnesium Deficiency

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From acid rain to magnesium deficiency

Acid rain not only damages forests, but also the soil. Fertilizers become necessary - yet fertilizer often contains too little magnesium. Soils poor in magnesium are the result.

Animals suffer: the tetany occurring early in the year in grazing animals is not infrequently fatal without magnesium injections. Humans also suffer depletion as a result because soil products or foods contain too little magnesium.

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Magnesium Deficiency

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Magnesium deficiency in humans

During all the phases of magnesium circulation within the body, there are factors which may lead of magnesium deficiency:

 note.gif (897 bytes) Impoverished foodstuffs lead, in a similar manner as dieting or other unbalanced nutrition to a reduced magnesium intake.

 note.gif (897 bytes) In addition, impaired absorption and

 note.gif (897 bytes) increased excretion number among the causes of magnesium deficiency in humans.

 

full spectrum mineral analysis

Increased  Magnesium   Requirements

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According to age and living conditions, increased magnesium requirements may occur in humans.  We have already mentioned the greater need during lactation and fasting diets. Magnesium replacement therapy may also, however, become necessary in individuals placed under professional stress or practicing active sport. In addition, magnesium is also employed in cardiac patients, in order to compensate for the increased magnesium excretion under diuretics or digitalis treatment.

 note.gif (897 bytes)

The technical information in this web site is not intended to recommend treatment or make specific diagnosis based on such data. It is intended for professional informational purposes, (from current medical literature), to assist practitioners in choosing appropriate protocols and modalities. Decisions on patient care should be based on all laboratory tests, health histories and clinical evaluations.

full spectrum mineral analysis

The Complex Symptoms of Mineral Deficiency and Imbalance

Continue to Page 2

 

IntraCellular Diagnostics, Inc.

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Medford, OR   97504

Tel. 541-245-3212 

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