Why Use Buccal Cells?

Journey to Inner Space

1. Research has shown that sublingual epithelial cells correlate well with deep body tissue such as heart tissue taken during bypass surgery and skeletal muscle biopsies. Additionally, NASA studies of muscle and bone changes in space correlate with sublingual epithelial cells.

2. Buccal cells have high correlation between altered mineral levels and pathophysiological conditions in multiple medical syndromes.

3. Sublingual cells provide new and important information as to the status of cardiac mineral electrolytes in patients with cardiovascular disease.

4. Sublingual epithelial cells offer a rapidly renewing, homogeneous cell population that reflects current total body intracellular mineral status.

5. Buccal cells have a high cytoplasm to nucleus structure facilitating mineral analysis. Cells contain full metabolic biochemical pathways.

6. Blood and urine levels of minerals and ions DO NOT necessarily reflect what is happening in the working cellular tissues.

7. Tissue cells contain 99% or more of the body’s magnesium and potassium, while serum contains only 1% of total.

8. Low intracellular tissue levels of mineral electrolytes may exist while the serum levels appear normal.

9. Using buccal cells in conjunction with Analytical Scanning Electron Microscopy makes ICD's ExaTest™  the most sensitive diagnostic medium for intracellular tissue measurement of light elements.

10. With ExaTest™ technology, the physician may monitor metabolic changes and the patient's response to therapy. You may routinely detect low levels of magnesium and potassium or elevated calcium and phosphorus. Calcification of cardiac and body tissue as calcium mobilizes from the bones to soft tissue may be an early sign of CAD and/or osteoporosis.

11. Buccal cells are safe, easy to obtain and use as a smear on specially prepared slides. Fixed specimens have a long life and do not deteriorate in transit.

ICD's EXA™  Test Is…

1. a proven procedure using rapidly metabolizing sublingual (buccal) cells of the oral cavity to reflect very fast tissue changes of vital minerals inside the body. 

2. a reproducible and reliable method allowing the practitioner to monitor and screen cellular mineral balance objectively and repeatedly in order to follow the patient metabolic physical status.

3. the world's first reference test for tissue mineral electrolytes, and your solution to measuring dynamic intracellular mineral levels.

*See our Research and Reference section.

IntraCellular Diagnostics, Inc.



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